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Seroconversion in household members of COVID-19 outpatients – one in three got infected

By June 22, 2020 June 23rd, 2020 No Comments

A study from Bergen shows higher household secondary attack rate of Covid-19 than a Chinese study.

We read with interest the Article by Qifang Bi and colleagues, in which they reported a household secondary attack rate, as detected by repeated RT-PCR tests, of approximately 11%.

We have found substantially higher attacks rates in western Norway through detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Of 158 cases, 125 (79%) tested positive for antibodies and 12 (8%) were defined as borderline.

In 77 household members, 24 (31%) tested positive and two (3%) were borderline. Our results show that detection of seroconversion might provide a more accurate picture of attack rates in households than intermittent RT-PCR testing.

Read the full study in the Lancet Infectious Diseases: Seroconversion in household members of COVID-19 outpatients